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D 1,000 IU D3 Mega D

When vitamin D is chronically deficient, 1,000 IU per day is the basic supplementation level recommended. Most bloodwork on patients will dictate supplementation between 1,000 - 6,000 IU per day.



Research

  Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Alt Med Rev. 2008;13(1):6-20.
  This is an extremely useful review article on vitamin D. The multiple conditions that may develop due to vitamin D deficiency are described. Supplementation amounts for all age groups and special populations are outlined.
  Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008;87(suppl):1080S-86S.
  Dr. Holick is a noted authority on vitamin D and is lead author in this excellent review on vitamin D deficiency.
  Ngo DT et al. Does vitamin D modulate asymmetric dimethylarginine and C-reactive protein concentrations? Am J Med. 2010;123:335-41.
  C-reactive protein is a general marker of systemic inflammation, while endothelial nitric oxide reduces hypertension and promotes vasorelaxation. The study found that low 25-hydroxyvitamin D3 concentrations are associated with increases in both high-sensitivity C-reactive protein and asymmetric dimethylarginine that inhibits endothelial nitric oxide.
  Hathcock JN et al. Risk assessment for vitamin D. Am J Clin Nutr. 2007;85:6-18.
  The purpose of this review article is to identify the appropriate upper limit for vitamin intake, which typically applies to supplemental levels as the food supply naturally contains little vitamin D. The authors identify 10,000 IU as the tolerable upper limit, which amounts to 250 mcg.
  Holick MF. Vitamin D deficiency: what a pain it is. Mayo Clin Proc. 2003;78:1457-59.
  An excellent review of how vitamin D deficiency can promote musculoskeletal pain.
  Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc. 2003;78:1463-70.
  The prevalence of hypovitaminosis D was unexpectedly high in this population of nonelderly, nonhousebound, primary care outpatients with persistent, nonspecific musculoskeletal pain refractory to standard pharmaceutical agents. Of all patients, 93% (140/150) had deficient levels of vitamin D (mean, 12.08 ng/mL). Normal level is 32-100 ng/mL.
  Schwalfenberg G. Improvement of chronic back pain or failed back surgery with vitamin D repletion: a case series. J Am Board Fam Med. 2009;22:69-74.
  This article reviews 6 selected cases of improvement/resolution of chronic back pain or failed back surgery after vitamin D repletion in a Canadian family practice setting. Vitamin D insufficiency is common; repletion of vitamin D to normal levels in patients who have chronic low back pain or have had failed back surgery may improve quality of life or, in some cases, result in complete resolution of symptoms.
  Cannell JJ. Vitamin D Council Newsletter. March, 2007. Vitamin D and athletic performance.
  Dr. Cannell reviews numerous articles that span from 1938-2007 on the topic of vitamin D and athletic performance. http://www.vitamindcouncil.org/
  Cannell JJ. Epidemic influenza and vitamin D. Epidemiol Infect. 2006;134:1129-40.
  This article focuses on the importance of vitamin D and immune function. Emerging research demonstrates that vitamin D deficiency can promote viral and bacterial infections.
  Gombart AF. The vitamin D-antimicrobial peptide pathway and its role in protection against infect. Future Microbiology. 2009;4(9):1151-65.
  This article focuses on the importance of vitamin D and immune function. Emerging research demonstrates that vitamin D deficiency can promote viral and bacterial infections.
  Urashima M et al. Randomized trial of vitamin D supplementation to prevent seasonal in?uenza A in schoolchildren. Am J Clin Nutr. First published ahead of print March 10, 2010 as doi: 10.3945/ajcn.2009.29094.
  This article focuses on the importance of vitamin D and immune function. Emerging research demonstrates that vitamin D deficiency can promote viral and bacterial infections.
About Us
Founded in 1924, Anabolic Laboratories is a pharmaceutical manufacturer of clinically dispensed nutritional products for the licensed health care professional.

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